Laboratory research material

TB-500 10mg

£29.99

TB-500 10mg: the N-acetylated thymosin β4 fragment (17–23), Ac-LKKTETQ, supplied as a lyophilised powder in a single sealed vial for in-vitro laboratory research. Independent analytical reports are listed on the CoA page. For laboratory research use only.

  • Same-day dispatch on orders before 3pm, Mon–Fri
  • Royal Mail Tracked 24, free UK delivery on orders of £50 or more
  • Certificates of analysis published on our CoA page
  • Laboratory research use only; 18+ to purchase
Key Features
  • Form: Lyophilised peptide powder
  • Quantity: 1 sealed vial, 10mg labelled
  • Compound: TB-500, thymosin β4 fragment (17–23), Ac-LKKTETQ
  • Intended use: Laboratory research only

Safety information: Not intended for human or veterinary use. Use appropriate laboratory safety procedures when handling.

TB-500 10mg should only be used in laboratory settings by qualified personnel.

Ensure all experimental procedures comply with local and institutional regulations.

This peptide is supplied for research and scientific study purposes only.

Janoshik test #125456 was run on one vial labelled TB-500 10mg. The report lists the result as “TB-500 (TB4)” and the request as “TB4/TB-500/TB4(17-23) analysis”, with a measured content of 12.09 mg against the 10mg stated on the label and a purity of 99.944%. View the report on janoshik.com.

The report covers one vial and does not state the analytical method or which peptide sequence was quantified. Purity and measured content are different results.

Product Details

TB-500 10mg

TB-500 is the name used in the research literature for a synthetic N-acetylated peptide fragment of thymosin β4 (Tβ4): the seven-amino-acid sequence Ac-LKKTETQ, corresponding to residues 17–23 of the 43-amino-acid Tβ4 protein. Ascend Peptides UK supplies TB-500 10mg as a lyophilised powder in a single sealed vial, for in-vitro laboratory research only.

At a glance

  • Quantity10mg
  • FormatLyophilized peptide powder
  • Intended useResearch use only

Reference Chemistry

  • Name: TB-500; thymosin β4 fragment (17–23), N-acetylated
  • Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH (Ac-LKKTETQ)
  • Length: 7 amino acids
  • Molecular formula: C38H68N10O14 (free peptide)
  • Molecular weight: 889.0 g/mol (free peptide)
  • CAS number: 885340-08-9
  • PubChem CID: 62707662
  • Quantity: 10mg per vial (labelled)
  • Form: Lyophilised powder, single sealed vial
  • Intended purpose: Laboratory research only
  • Category: Recovery research peptides

These are reference values for the TB-500 molecule (PubChem; Cayman Chemical item 45081, supplied there as the acetate salt). They describe the compound, not test results for a particular vial. A salt form such as the acetate has a higher formula weight than the free peptide. Confirmation of the exact form supplied in Ascend vials is being obtained from the manufacturer.

TB-500 and Thymosin β4 Are Different Molecules

Full-length thymosin β4 is a 43-amino-acid protein (UniProt P62328; about 4.96 kDa) that binds monomeric G-actin and regulates actin polymerisation. TB-500 is a seven-residue fragment taken from the actin-binding region of that protein. Much of the published cell-migration and actin research was carried out with full-length Tβ4, and those findings do not automatically apply to the fragment. The evidence base for the fragment on its own is smaller and largely preclinical. A fuller explanation is in What Is TB-500?, and laboratory background is in the TB-500 10mg laboratory guide.

Testing and Documentation

Independent analytical reports for TB-500 10mg are published on the CoA page and in the Certificate of Analysis section of this page. Each report applies to the vial and batch it names, so when stock changes the testing record is updated rather than this description. Purity and measured content are different results, and a report only confirms the analyses it lists.

Storage and Handling

Storage requirements for this product are being confirmed with the manufacturer. Please contact ASCEND for the information held for the current stock.

Anti-Doping Status

Thymosin β4 and its derivatives, including TB-500, are listed under section S2 of the WADA Prohibited List, which is revised annually.

References

  • TB-500 compound record, CID 62707662 (C38H68N10O14, 889.0 g/mol; CAS 885340-08-9). PubChem. PubChem 62707662
  • TB-500 (acetate), item 45081: Ac-LKKTETQ-OH, formula weight 889.0 (free peptide). Cayman Chemical product information. Cayman Chemical 45081
  • Thymosin beta-4, human (TMSB4X), UniProt P62328: mature chain residues 2–44, N-acetylserine. UniProt P62328
Disclaimer

For in-vitro laboratory research only. Not for human consumption, therapeutic, diagnostic or clinical use.

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