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MOTS-C 10mg research peptide UK is a mitochondria-derived 16-amino acid peptide encoded in mitochondrial 12S rRNA, studied for AMPK pathway activation and mitochondria-to-nucleus communication in UK laboratories. ≥98% purity. Janoshik tested. Same-day dispatch. Research use only.
Safety Information: Not intended for human or veterinary use. Use appropriate laboratory safety procedures when handling.
MOTS-C 10mg should only be used in laboratory settings by qualified personnel.
Ensure all experimental procedures comply with local and institutional regulations.
This peptide is supplied for research and scientific study purposes only.
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MOTS-C 10mg Research Peptide UK
MOTS-C 10mg (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a 16-amino acid peptide encoded not by nuclear DNA but by the mitochondrial genome, specifically within the 12S rRNA gene. This mitochondrial origin is the defining scientific characteristic that distinguishes mots-c 10mg research peptide from every other compound in the Ascend Peptides UK range and from all other UK research peptides. No other compound in this market is derived from the mitochondrial genome.
The primary research mechanism of MOTS-C involves cellular stress-triggered translocation from the mitochondria to the nucleus, where it regulates gene expression through AMPK (AMP-activated protein kinase)-dependent pathways. AMPK is a central energy-sensing enzyme that coordinates metabolic responses to cellular energy status and is one of the most studied kinases in metabolic biology research. MOTS-C-driven AMPK activation affects downstream gene expression governing energy homeostasis, glucose uptake regulation, mitochondrial biogenesis signalling, and antioxidant defence pathway coordination.
This mitochondria-to-nucleus communication — sometimes described as mitochondrial retrograde signalling — is an active and rapidly evolving research field. MOTS-C belongs to the small group of mitochondria-derived peptides (MDPs) that have been identified and characterised in published literature, and it represents the primary research tool for MOTS-C-specific pathway investigation. There is no mechanistic overlap between mots-c research and any other compound in the Ascend Peptides UK range.
The 10mg format is the entry format for MOTS-C research, appropriate for pilot studies, method validation, initial AMPK pathway investigations, and first-time mitochondrial peptide research. For established programmes requiring high-throughput assays, institutional supply across multiple researchers, or extended single-batch longitudinal studies, MOTS-C 40mg provides the bulk format with identical compound and purity standard.
All batches of MOTS-C 10mg are independently tested by Janoshik. HPLC purity confirmed at greater than or equal to 98%. LC-MS molecular identity confirmed. Full Certificate of Analysis publicly verifiable.
For laboratory handling purposes, MOTS-C may be reconstituted using sterile aqueous solutions such as bacteriostatic water depending on experimental requirements. Store lyophilised material at -20°C.
DISCLAIMER: For in-vitro laboratory research only. Not for human consumption, therapeutic, diagnostic, or clinical use. Not classified as a medicinal product by the MHRA.
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All products sold by Ascend Peptides UK are intended strictly for laboratory research purposes only. Not intended for human consumption or therapeutic use of any kind.