MT-2 10mg (Melanotan II)

MT-2 10mg Research Peptide UK (Melanotan II)

MT-2 10mg (Melanotan II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte stimulating hormone (alpha-MSH). Unlike MT-1 10mg (Afamelanotide), which is selective for MC1R, MT-2 is a non-selective melanocortin agonist activating four receptor subtypes simultaneously: MC1R (melanocytes, pigmentation research), MC3R (immune modulation and energy balance research), MC4R (energy homeostasis and appetite regulation research), and MC5R (exocrine gland secretion research). The mt2 10mg research peptide is the appropriate compound for broad melanocortin system investigations where multi-receptor pathway activation is the research objective.

The multi-receptor activation profile of MT-2 is both its defining research characteristic and its primary experimental design consideration. Researchers must be specific about which receptor subtype(s) their study addresses. When the research question is specific to MC1R biology in isolation — pigmentation, melanocyte receptor pharmacology, UV response modelling — MT-1 10mg provides the selective reference compound without confounding activity at MC3R, MC4R, and MC5R. When the research question concerns broad melanocortin system activity, appetite and energy homeostasis pathways via MC4R, or multi-receptor activation dynamics, MT-2 10mg is the appropriate selection.

MC4R represents one of the most widely studied individual applications of MT-2 in laboratory research. It is studied in preclinical trials that MC4R is predominantly expressed in hypothalamic nuclei and has extensive published documentation of its role in energy homeostasis and appetite regulation pathways. Researchers specifically investigating MC4R-mediated biology often use MT-2 as the non-selective melanocortin agonist probe, with multi-receptor activity accounted for in the experimental design.

For a complete side-by-side receptor comparison covering when to select MT-1 versus MT-2 and what each receptor subtype contributes to the data, see the MT-1 10mg research guide and MT-2 10mg research guide on the Ascend Peptides UK blog. For comparative melanocortin receptor studies requiring both compounds, MT-1 10mg is available separately from Ascend Peptides UK.

All batches independently tested by Janoshik. HPLC greater than or equal to 98%. LC-MS confirmed. Verifiable CoA.

For laboratory handling purposes, MT-2 may be reconstituted using sterile aqueous solutions such as bacteriostatic water depending on experimental requirements

WADA Status: Listed as a prohibited substance under anti-doping regulations.

DISCLAIMER: For in-vitro research only. Not an MHRA-licensed medicine.